Chemomechanical Simulation of Microtubule Dynamics With Explicit Lateral Bond Dynamics

We introduce and parameterize a chemomechanical model of microtubule dynamics on the dimer level, which is based on the allosteric tubulin model and includes attachment, detachment and hydrolysis of tubulin dimers as well as stretching of lateral bonds, bending at longitudinal junctions, and the pos...

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Bibliographic Details
Main Authors: Matthias Schmidt, Jan Kierfeld
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Physics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphy.2021.673875/full