Constitutive Activity among Orphan Class-A G Protein Coupled Receptors.

The purpose of this study was to evaluate the extent of constitutive activity among orphan class-A G protein coupled receptors within the cAMP signaling pathway. Constitutive signaling was revealed by changes in gene expression under control of the cAMP response element. Gene expression was measured...

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Bibliographic Details
Main Authors: Adam L Martin, Michael A Steurer, Robert S Aronstam
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4575141?pdf=render