Statistical Methods for Evaluating DNA Methylation as a Marker for Early Detection or Prognosis

We summarize standard and novel statistical methods for evaluating the classification accuracy of DNA methylation markers. The choice of method will depend on the type of marker studied (qualitative/quantitative), the number of markers, and the type of outcome (time-invariant/time-varying). A minimu...

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Bibliographic Details
Main Authors: Todd A. Alonzo, Kimberly D. Siegmund
Format: Article
Language:English
Published: Hindawi Limited 2007-01-01
Series:Disease Markers
Online Access:http://dx.doi.org/10.1155/2007/308573