Antineoplastic Effect of Lenvatinib and Vandetanib in Primary Anaplastic Thyroid Cancer Cells Obtained From Biopsy or Fine Needle Aspiration

Antineoplastic Effect of Lenvatinib and Vandetanib in Primary Anaplastic Thyroid Cancer Cells Obtained From Biopsy or Fine Needle Aspiration

Anaplastic thyroid carcinoma (ATC) is a malignant tumor of the thyroid gland, infrequent but with a very poor prognosis, as it rapidly causes death (mean survival of about 6 months). ATC treatment includes a multimodal protocol consisting of surgery, chemotherapy (doxorubicin and cisplatin), and hyp...

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Bibliographic Details
Main Authors: Silvia Martina Ferrari, Concettina La Motta, Giusy Elia, Francesca Ragusa, Ilaria Ruffilli, Luca Quattrini, Sabrina Rosaria Paparo, Simona Piaggi, Armando Patrizio, Salvatore Ulisse, Enke Baldini, Gabriele Materazzi, Poupak Fallahi, Alessandro Antonelli
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Endocrinology
Subjects:
anaplastic thyroid cancer
fine needle aspiration
lenvatinib
primary anaplastic thyroid cancer cells
tyrosine kinase inhibitors
vandetanib
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2018.00764/full

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https://www.frontiersin.org/article/10.3389/fendo.2018.00764/full

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