Retinoic Acid Sensitivity of Triple-Negative Breast Cancer Cells Characterized by Constitutive Activation of the notch1 Pathway: The Role of Rarβ

Retinoic Acid Sensitivity of Triple-Negative Breast Cancer Cells Characterized by Constitutive Activation of the notch1 Pathway: The Role of Rarβ

Triple-negative breast cancer (<i>TNBC</i>) is a heterogeneous disease that lacks effective therapeutic options. In this study, we profile eighteen <i>TNBC</i> cell lines for their sensitivity to the anti-proliferative action of all-trans retinoic acid (ATRA). The only three...

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Bibliographic Details
Main Authors: Gabriela Paroni, Adriana Zanetti, Maria Monica Barzago, Mami Kurosaki, Luca Guarrera, Maddalena Fratelli, Martina Troiani, Paolo Ubezio, Marco Bolis, Arianna Vallerga, Federica Biancardi, Mineko Terao, Enrico Garattini
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Cancers
Subjects:
retinoic acid
breast cancer
triple-negative
Notch1
RARbeta
Online Access:https://www.mdpi.com/2072-6694/12/10/3027

Internet

https://www.mdpi.com/2072-6694/12/10/3027

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