T Cell Targeting by Anthrax Toxins: Two Faces of the Same Coin

T Cell Targeting by Anthrax Toxins: Two Faces of the Same Coin

Bacillus anthracis, similar to other bacterial pathogens, has evolved effective immune evasion strategies to prolong its survival in the host, thus ensuring the unchecked spread of the infection. This function is subserved by lethal (LT) and edema (ET) toxins, two exotoxins produced by vegetative an...

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Bibliographic Details
Main Authors: Silvia Rossi Paccani, Cosima T. Baldari
Format: Article
Language:English
Published: MDPI AG 2011-06-01
Series:Toxins
Subjects:
lethal toxin
edema toxin
T cell
Th subset
TCR signaling
cAMP
MAP kinases
immunosuppression
immunodeviating
Online Access:http://www.mdpi.com/2072-6651/3/6/660/

Internet

http://www.mdpi.com/2072-6651/3/6/660/

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