A Celecoxib Derivative Eradicates Antibiotic-Resistant <i>Staphylococcus aureus</i> and Biofilms by Targeting YidC2 Translocase
The treatment of <i>Staphylococcus aureus</i> infections is impeded by the prevalence of MRSA and the formation of persisters and biofilms. Previously, we identified two celecoxib derivatives, Cpd36 and Cpd46, to eradicate MRSA and other staphylococci. Through whole-genome resequencing,...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-12-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/21/23/9312 |