CAN1 Arginine Permease Deficiency Extends Yeast Replicative Lifespan via Translational Activation of Stress Response Genes

Transcriptional regulation plays an important role in the control of gene expression during aging. However, translation efficiency likely plays an equally important role in determining protein abundance, but it has been relatively understudied in this context. Here, we used RNA sequencing (RNA-seq)...

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Bibliographic Details
Main Authors: Carine Beaupere, Brian M. Wasko, Jared Lorusso, Brian K. Kennedy, Matt Kaeberlein, Vyacheslav M. Labunskyy
Format: Article
Language:English
Published: Elsevier 2017-02-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S221112471730147X