Repeated Fractions of X-Radiation to the Breast Fat Pads of Mice Augment Activation of the Autotaxin-Lysophosphatidate-Inflammatory Cycle

Repeated Fractions of X-Radiation to the Breast Fat Pads of Mice Augment Activation of the Autotaxin-Lysophosphatidate-Inflammatory Cycle

Breast cancer patients are usually treated with multiple fractions of radiotherapy (RT) to the whole breast after lumpectomy. We hypothesized that repeated fractions of RT would progressively activate the autotaxin−lysophosphatidate-inflammatory cycle. To test this, a normal breast fat pad...

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Bibliographic Details
Main Authors: Guanmin Meng, Melinda Wuest, Xiaoyun Tang, Jennifer Dufour, YuanYuan Zhao, Jonathan M. Curtis, Todd P. W. McMullen, David Murray, Frank Wuest, David N. Brindley
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Cancers
Subjects:
adiponectin
adipose tissue
breast cancer
chemokines
cytokines
radiotherapy
Online Access:https://www.mdpi.com/2072-6694/11/11/1816

Internet

https://www.mdpi.com/2072-6694/11/11/1816

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