Haemophilus parasuis Infection Disrupts Adherens Junctions and Initializes EMT Dependent on Canonical Wnt/β-Catenin Signaling Pathway

Haemophilus parasuis Infection Disrupts Adherens Junctions and Initializes EMT Dependent on Canonical Wnt/β-Catenin Signaling Pathway

In this study, animal experimentation verified that the canonical Wnt/β-catenin signaling pathway was activated under a reduced activity of p-β-catenin (Ser33/37/Thr41) and an increased accumulation of β-catenin in the lungs and kidneys of pigs infected with a highly virulent strain of H. parasuis....

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Bibliographic Details
Main Authors: Kexin Hua, Yangjie Li, Hufeng Zhou, Xueying Hu, Yushan Chen, Rongrong He, Rui Luo, Rui Zhou, Dingren Bi, Hui Jin
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Haemophilus parasuis
Wnt/β-catenin
E-cadherin
adherens junctions
EMT
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2018.00324/full

Internet

https://www.frontiersin.org/article/10.3389/fcimb.2018.00324/full

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