Neuroprotection from NMDA excitotoxic lesion by Cu/Zn superoxide dismutase gene delivery to the postnatal rat brain by a modular protein vector

<p>Abstract</p> <p>Background</p> <p>Superoxide mediated oxidative stress is a key neuropathologic mechanism in acute central nervous system injuries. We have analyzed the neuroprotective efficacy of the transient overexpression of antioxidant enzyme Cu/Zn Superoxide di...

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Bibliographic Details
Main Authors: Castellano Bernardo, Villaverde Antoni, González Pau, Arís Anna, Acarin Laia, Peluffo Hugo, González Berta
Format: Article
Language:English
Published: BMC 2006-04-01
Series:BMC Neuroscience
Online Access:http://www.biomedcentral.com/1471-2202/7/35