Establishing a Case for Anti-complement Therapy in Membranous Nephropathy

Establishing a Case for Anti-complement Therapy in Membranous Nephropathy

Introduction: Membranous nephropathy (MN) is a common cause of adult nephrotic syndrome that progresses to end-stage kidney disease in up to 40% of cases. It is an autoimmune disease characterized by glomerular subepithelial deposits containing IgG. In experimental MN, these deposits activate comple...

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Bibliographic Details
Main Authors: Isabelle Ayoub, John P. Shapiro, Huijuan Song, Xiaolan Lily Zhang, Samir Parikh, Salem Almaani, Sethu Madhavan, Sergey V. Brodsky, Anjali Satoskar, Cherri Bott, Lianbo Yu, Michael Merchant, John Klein, Juan M. Mejia-Vilet, Tibor Nadasdy, Dan Birmingham, Brad H. Rovin
Format: Article
Language:English
Published: Elsevier 2021-02-01
Series:Kidney International Reports
Subjects:
complement protein
membranous nephropathy
proteomic analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S2468024920317897

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http://www.sciencedirect.com/science/article/pii/S2468024920317897

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