Hydroxy-epoxide and keto-epoxide derivatives of linoleic acid activate trigeminal neurons

Endogenous lipid mediators are proposed to contribute to headache and facial pain by activating trigeminal neurons (TN). We recently identified 11-hydroxy-epoxide- and 11-keto-epoxide derivatives of linoleic acid (LA) that are present in human skin and plasma and potentially contribute to nociceptio...

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Bibliographic Details
Main Authors: Suzanne Doolen, Gregory S. Keyes, Christopher E. Ramsden
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Neurobiology of Pain
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2452073X20300040