Dual regulation by pairs of cyclin-dependent protein kinases and histone deacetylases controls G1 transcription in budding yeast.

Dual regulation by pairs of cyclin-dependent protein kinases and histone deacetylases controls G1 transcription in budding yeast.

START-dependent transcription in Saccharomyces cerevisiae is regulated by two transcription factors SBF and MBF, whose activity is controlled by the binding of the repressor Whi5. Phosphorylation and removal of Whi5 by the cyclin-dependent kinase (CDK) Cln3-Cdc28 alleviates the Whi5-dependent repres...

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Bibliographic Details
Main Authors: Dongqing Huang, Supipi Kaluarachchi, Dewald van Dyk, Helena Friesen, Richelle Sopko, Wei Ye, Nazareth Bastajian, Jason Moffat, Holly Sassi, Michael Costanzo, Brenda J Andrews
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-09-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC2730531?pdf=render

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http://europepmc.org/articles/PMC2730531?pdf=render

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