CAR T Cell Toxicity: Current Management and Future Directions

Abstract. By late 2018, 2 chimeric antigen receptor T (CAR T) cell products have been approved by US and European regulatory authorities. Tisagenlecleucel (Kymriah, Novartis) is indicated in the treatment of patients up to 25 years of age with B-cell acute lymphoblastic leukemia (ALL) that is refrac...

Full description

Bibliographic Details
Main Authors: Lucrecia Yáñez, Miriam Sánchez-Escamilla, Miguel-Angel Perales
Format: Article
Language:English
Published: Wolters Kluwer 2019-04-01
Series:HemaSphere
Online Access:http://journals.lww.com/10.1097/HS9.0000000000000186