Polygenic risk for schizophrenia and associated brain structural changes: A systematic review

Background: Genome wide association studies (GWAS) of schizophrenia allow the generation of Polygenic Risk Scores (PRS). PRS can be used to determine the contribution to altered brain structures in this disorder, which have been well described. However, findings from studies using PRS to predict bra...

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Bibliographic Details
Main Authors: C. van der Merwe, R. Passchier, M. Mufford, R. Ramesar, S. Dalvie, D.J. Stein
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Comprehensive Psychiatry
Online Access:http://www.sciencedirect.com/science/article/pii/S0010440X18301998