Staphylococcus aureus Membrane-Derived Vesicles Promote Bacterial Virulence and Confer Protective Immunity in Murine Infection Models

Staphylococcus aureus Membrane-Derived Vesicles Promote Bacterial Virulence and Confer Protective Immunity in Murine Infection Models

Staphylococcus aureus produces membrane-derived vesicles (MVs), which share functional properties to outer membrane vesicles. Atomic force microscopy revealed that S. aureus-derived MVs are associated with the bacterial surface or released into the surrounding environment depending on bacterial grow...

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Bibliographic Details
Main Authors: Fatemeh Askarian, John D. Lapek, Mitesh Dongre, Chih-Ming Tsai, Monika Kumaraswamy, Armin Kousha, J. Andrés Valderrama, Judith A. Ludviksen, Jorunn P. Cavanagh, Satoshi Uchiyama, Tom E. Mollnes, David J. Gonzalez, Sun N. Wai, Victor Nizet, Mona Johannessen
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Microbiology
Subjects:
Staphylococcus aureus
membrane-derived vesicles
proteomics
systemic infection
protective immunity
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2018.00262/full

Internet

http://journal.frontiersin.org/article/10.3389/fmicb.2018.00262/full

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