Induction of ferroptosis in response to graphene quantum dots through mitochondrial oxidative stress in microglia

Induction of ferroptosis in response to graphene quantum dots through mitochondrial oxidative stress in microglia

Abstract Background Graphene quantum dots (GQDs) provide a bright prospect in the biomedical application because they contain low-toxic compounds and promise imaging of deep tissues and tiny vascular structures. However, the biosafety of this novel QDs has not been thoroughly evaluated, especially i...

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Bibliographic Details
Main Authors: Tianshu Wu, Xue Liang, Xi Liu, Yimeng Li, Yutong Wang, Lu Kong, Meng Tang
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Particle and Fibre Toxicology
Subjects:
ROS
Iron overload
GSH depletion
Lipid peroxidation
Mitochondrial dysfunction
Online Access:http://link.springer.com/article/10.1186/s12989-020-00363-1

Internet

http://link.springer.com/article/10.1186/s12989-020-00363-1

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