Uremia does not affect neointima formation in mice

Abstract Atherosclerotic cardiovascular disease is a major complication of chronic kidney disease (CKD). CKD leads to uremia, which modulates the phenotype of aortic smooth muscle cells (SMCs). Phenotypic modulation of SMCs plays a key role in accelerating atherosclerosis. We investigated the hypoth...

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Bibliographic Details
Main Authors: Annemarie Aarup, Carsten H. Nielsen, Line S. Bisgaard, Ilze Bot, Henrik H. El-Ali, Andreas Kjaer, Lars B. Nielsen, Tanja X. Pedersen
Format: Article
Language:English
Published: Nature Publishing Group 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-06816-6