Secreted Rv1768 From RD14 of Mycobacterium tuberculosis Activates Macrophages and Induces a Strong IFN-γ-Releasing of CD4+ T Cells

Secreted Rv1768 From RD14 of Mycobacterium tuberculosis Activates Macrophages and Induces a Strong IFN-γ-Releasing of CD4+ T Cells

As the first line defensive mediators against Mycobacterium tuberculosis (M.tb) infection, macrophages can be modulated by M.tb to influence innate and adaptive immunity. Recently, we have identified several potential immunodominant T-cell antigens from the region of deletion (RD) of M.tb H37Rv, inc...

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Bibliographic Details
Main Authors: Chun-Hui Yuan, Simin Zhang, Feiyan Xiang, Hongjian Gong, Qian Wang, Yan Chen, Wei Luo
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Rv1768
macrophage
tuberculosis
enzyme-linked immunospot
diagnosis
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2019.00341/full

Internet

https://www.frontiersin.org/article/10.3389/fcimb.2019.00341/full

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