On the relative relevance of subject-specific geometries and degeneration-specific mechanical properties for the study of cell death in human intervertebral disc models

On the relative relevance of subject-specific geometries and degeneration-specific mechanical properties for the study of cell death in human intervertebral disc models

Capturing patient- or condition-specific intervertebral disc (IVD) properties in finite element models is outmost important in order to explore how biomechanical and biophysical processes may interact in spine diseases. However, disc degenerative changes are often modelled through equations similar...

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Bibliographic Details
Main Authors: Andrea eMalandrino, Jose Maria ePozo, Isaac eCastro-Mateos, Alejandro F Frangi, Marc M van Rijsbergen, Keita eIto, Hans-Joachim eWilke, Tien Tuan eDao, Marie-Christine eHo Ba Tho, Jerome eNoailly
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-02-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Intervertebral Disc Degeneration
Finite element modelling
lumbar spine
poroelasticity
Damage model
Subject-specific modelling
Online Access:http://journal.frontiersin.org/Journal/10.3389/fbioe.2015.00005/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fbioe.2015.00005/full

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