Increased expression of the SNARE accessory protein Munc18c in lipid-mediated insulin resistance

Increased expression of the SNARE accessory protein Munc18c in lipid-mediated insulin resistance

Fatty acids inhibit insulin-mediated glucose metabolism in skeletal muscle, an effect largely attributed to defects in insulin-mediated glucose transport. Insulin-resistant mice transgenic for the overexpression of lipoprotein lipase (LPL) in skeletal muscle were used to examine the molecular mechan...

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Bibliographic Details
Main Authors: Isabel R. Schlaepfer, Leslie K. Pulawa, Luis D.M. C-B. Ferreira, David E. James, Warren H. Capell, Robert H. Eckel
Format: Article
Language:English
Published: Elsevier 2003-06-01
Series:Journal of Lipid Research
Subjects:
GLUT4
muscle
soluble N-ethylmaleimide-sensitive factor attachment protein receptor
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520311184

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http://www.sciencedirect.com/science/article/pii/S0022227520311184

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