Identification of cancer-specific motifs in mimotope profiles of serum antibody repertoire

Identification of cancer-specific motifs in mimotope profiles of serum antibody repertoire

Abstract Background For fighting cancer, earlier detection is crucial. Circulating auto-antibodies produced by the patient’s own immune system after exposure to cancer proteins are promising bio-markers for the early detection of cancer. Since an antibody recognizes not the whole antigen but 4–7 cri...

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Bibliographic Details
Main Authors: Ekaterina Gerasimov, Alex Zelikovsky, Ion Măndoiu, Yurij Ionov
Format: Article
Language:English
Published: BMC 2017-06-01
Series:BMC Bioinformatics
Subjects:
Random peptide phage display library
Early cancer detection
Immune response
Peptide motifs
Mimotope profile
Online Access:http://link.springer.com/article/10.1186/s12859-017-1661-5

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http://link.springer.com/article/10.1186/s12859-017-1661-5

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