Prep1, A Homeodomain Transcription Factor Involved in Glucose and Lipid Metabolism

Prep1, A Homeodomain Transcription Factor Involved in Glucose and Lipid Metabolism

The three-amino acid loop extension (TALE) homeodomain proteins are a family of transcription factor including the mammalian Pbx, MEIS and Prep proteins. TALE proteins can bind other transcription factors such as Pdx-1 and play an important role in the regulation of glucose metabolism. Experiments p...

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Bibliographic Details
Main Authors: Francesco Oriente, Giuseppe Perruolo, Ilaria Cimmino, Serena Cabaro, Antonietta Liotti, Michele Longo, Claudia Miele, Pietro Formisano, Francesco Beguinot
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Endocrinology
Subjects:
transcription factors
Prep1
TALE proteins
insulin signaling
diabetes mellitus
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2018.00346/full

Internet

https://www.frontiersin.org/article/10.3389/fendo.2018.00346/full

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