Human antigen R enhances the epithelial-mesenchymal transition via regulation of ZEB-1 in the human airway epithelium

Human antigen R enhances the epithelial-mesenchymal transition via regulation of ZEB-1 in the human airway epithelium

Abstract Background Increasing evidence suggests that human antigen R (HuR) is involved in the epithelial-mesenchymal transition (EMT) process of several diseases. However, the role of HuR in EMT in the airway epithelial cells of patients with COPD remains unclear. Methods BEAS-2B cells were culture...

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Bibliographic Details
Main Authors: Jian Sun, Xianmin Gu, Nan Wu, Pengju Zhang, Yi Liu, Shujuan Jiang
Format: Article
Language:English
Published: BMC 2018-06-01
Series:Respiratory Research
Subjects:
Chronic obstructive pulmonary disease
Cigarette smoke extract
Human antigen R
Epithelial–mesenchymal transition
Zinc finger E-box binding homeobox 1
Online Access:http://link.springer.com/article/10.1186/s12931-018-0805-0

Internet

http://link.springer.com/article/10.1186/s12931-018-0805-0

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