Molecular approaches to determine the multiplicity of Plasmodium infections

Molecular approaches to determine the multiplicity of Plasmodium infections

Abstract Multiplicity of infection (MOI), also termed complexity of infection (COI), is defined as the number of genetically distinct parasite strains co-infecting a single host, which is an important indicator of malaria epidemiology. PCR-based genotyping often underestimates MOI. Next generation s...

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Bibliographic Details
Main Authors: Daibin Zhong, Cristian Koepfli, Liwang Cui, Guiyun Yan
Format: Article
Language:English
Published: BMC 2018-04-01
Series:Malaria Journal
Subjects:
Malaria parasite
Multiplicity of infection
Molecular marker
Next generation sequencing
Amplicon ultra-deep sequencing
Single nucleotide polymorphism
Online Access:http://link.springer.com/article/10.1186/s12936-018-2322-5

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http://link.springer.com/article/10.1186/s12936-018-2322-5

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