Balancing the Photoreceptor Proteome: Proteostasis Network Therapeutics for Inherited Retinal Disease

The light sensing outer segments of photoreceptors (PRs) are renewed every ten days due to their high photoactivity, especially of the cones during daytime vision. This demands a tremendous amount of energy, as well as a high turnover of their main biosynthetic compounds, membranes, and proteins. Th...

Full description

Bibliographic Details
Main Authors: Siebren Faber, Ronald Roepman
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/10/8/557