Biologic Effects of Dopamine on Tumor Vasculature in Ovarian Carcinoma

Chronic sympathetic nervous system activation results in increased angiogenesis and tumor growth in orthotopic mouse models of ovarian carcinoma. However, the mechanistic effects of such activation on the tumor vasculature are not well understood. Dopamine (DA), an inhibitory catecholamine, regulat...

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Main Authors: Myrthala Moreno-Smith, Sun Joo Lee, Chunhua Lu, Archana S Nagaraja, Guangan He, Rajesha Rupaimoole, Hee Dong Han, Nicholas B Jennings, Ju-Won Roh, Masato Nishimura, Yu Kang, Julie K Allen, Guillermo N Armaiz, Koji Matsuo, Mian M K Shahzad, Justin Bottsford-Miller, Robert R Langley, Steve W Cole, Susan K Lutgendorf, Zahid H Siddik, Anil K Sood
Format: Article
Language:English
Published: Elsevier 2013-05-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S147655861380036X