LR Hunting: A Random Forest Based Cell–Cell Interaction Discovery Method for Single-Cell Gene Expression Data

LR Hunting: A Random Forest Based Cell–Cell Interaction Discovery Method for Single-Cell Gene Expression Data

Cell–cell interactions (CCIs) and cell–cell communication (CCC) are critical for maintaining complex biological systems. The availability of single-cell RNA sequencing (scRNA-seq) data opens new avenues for deciphering CCIs and CCCs through identifying ligand-receptor (LR) gene interactions between...

Full description

Bibliographic Details
Main Authors: Min Lu, Yifan Sha, Tiago C. Silva, Antonio Colaprico, Xiaodian Sun, Yuguang Ban, Lily Wang, Brian D. Lehmann, X. Steven Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Genetics
Subjects:
random forests
ligand-receptor interaction
cell–cell interaction
cell–cell communications
single-cell RNA-seq
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.708835/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2021.708835/full

Similar Items