Gamma-smooth muscle actin expression is associated with epithelial-mesenchymal transition and stem-like properties in hepatocellular carcinoma.

The prognosis of hepatocellular carcinoma (HCC) is hampered by frequent tumour recurrence and metastases. Epithelial-Mesenchymal Transition (EMT) is now recognized as a key process in tumour invasion, metastasis and the generation of cancer initiating cells. The morphological identification of EMT i...

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Bibliographic Details
Main Authors: Nassima Benzoubir, Charlotte Mussini, Charlène Lejamtel, Alexandre Dos Santos, Claire Guillaume, Christophe Desterke, Didier Samuel, Christian Bréchot, Marie-Françoise Bourgeade, Catherine Guettier
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4482489?pdf=render