Structural equation modeling for hypertension and type 2 diabetes based on multiple SNPs and multiple phenotypes.

Genome-wide association studies (GWAS) have been successful in identifying genetic variants associated with complex diseases. However, association analyses between genotypes and phenotypes are not straightforward due to the complex relationships between genetic and environmental factors. Moreover, m...

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Bibliographic Details
Main Authors: Saebom Jeon, Ji-Yeon Shin, Jaeyong Yee, Taesung Park, Mira Park
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0217189