Genomic Characterization Provides New Insights Into the Biosynthesis of the Secondary Metabolite Huperzine a in the Endophyte Colletotrichum gloeosporioides Cg01

Genomic Characterization Provides New Insights Into the Biosynthesis of the Secondary Metabolite Huperzine a in the Endophyte Colletotrichum gloeosporioides Cg01

A reliable source of Huperzine A (HupA) meets an urgent need due to its wide use in Alzheimer's disease treatment. In this study, we sequenced and characterized the whole genomes of two HupA-producing endophytes, Penicillium polonicum hy4 and Colletotrichum gloeosporioides Cg01, to clarify the...

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Bibliographic Details
Main Authors: Xincong Kang, Chichuan Liu, Pengyuan Shen, Liqin Hu, Runmao Lin, Jian Ling, Xingyao Xiong, Bingyan Xie, Dongbo Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Microbiology
Subjects:
endophyte
genome
differentially expressed genes
biosynthesis
histone modification
gene knockout
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.03237/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2018.03237/full

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