Rhein Protects Against Neurological Deficits After Traumatic Brain Injury in Mice via Inhibiting Neuronal Pyroptosis

Rhein Protects Against Neurological Deficits After Traumatic Brain Injury in Mice via Inhibiting Neuronal Pyroptosis

Neurological dysfunction provoked by traumatic brain injury (TBI) makes a huge impact on individual learning ability, memory level, social participation, and quality of life. Pyroptosis, the caspase-1-dependent cell death, which is associated with the release of numerous pro-inflammatory factors, pl...

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Bibliographic Details
Main Authors: Fangfang Bi, Huaifen Ma, Chen Ji, Cuicui Chang, Wenbo Liu, Keliang Xie
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Pharmacology
Subjects:
Rhein
traumatic brain injury
inflammatory cytokines
pyroptosis
neurological deficits
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.564367/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2020.564367/full

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