From Structural Variation of Gene Molecules to Chromatin Dynamics and Transcriptional Bursting

From Structural Variation of Gene Molecules to Chromatin Dynamics and Transcriptional Bursting

Transcriptional activation of eukaryotic genes is accompanied, in general, by a change in the sensitivity of promoter chromatin to endonucleases. The structural basis of this alteration has remained elusive for decades; but the change has been viewed as a transformation of one structure into anothe...

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Bibliographic Details
Main Authors: Hinrich Boeger, Robert Shelansky, Heta Patel, Christopher R. Brown
Format: Article
Language:English
Published: MDPI AG 2015-06-01
Series:Genes
Subjects:
chromatin dynamics
transcriptional bursting
gene expression noise
stochastic process
Online Access:http://www.mdpi.com/2073-4425/6/3/469

Internet

http://www.mdpi.com/2073-4425/6/3/469

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