Default Mode Network Structural Integrity and Cerebellar Connectivity Predict Information Processing Speed Deficit in Multiple Sclerosis

Default Mode Network Structural Integrity and Cerebellar Connectivity Predict Information Processing Speed Deficit in Multiple Sclerosis

Cognitive impairment affects about 50% of multiple sclerosis (MS) patients, but the mechanisms underlying this remain unclear. The default mode network (DMN) has been linked with cognition, but in MS its role is still poorly understood. Moreover, within an extended DMN network including the cerebell...

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Bibliographic Details
Main Authors: Giovanni Savini, Matteo Pardini, Gloria Castellazzi, Alessandro Lascialfari, Declan Chard, Egidio D’Angelo, Claudia A. M. Gandini Wheeler-Kingshott
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Cellular Neuroscience
Subjects:
default mode network (DMN)
cerebellum
multiple sclerosis (MS)
symbol digit modalities test (SDMT)
connectomics
tractography
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2019.00021/full

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https://www.frontiersin.org/article/10.3389/fncel.2019.00021/full

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