A Potential Role for Fructosamine-3-Kinase in Cataract Treatment

A Potential Role for Fructosamine-3-Kinase in Cataract Treatment

Cataracts are the major cause of blindness worldwide, largely resulting from aging and diabetes mellitus. Advanced glycation end-products (AGEs) have been identified as major contributors in cataract formation because they alter lens protein structure and stability and induce covalent cross-linking,...

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Bibliographic Details
Main Authors: Sander De Bruyne, Loes van Schie, Jonas Himpe, Filip De Somer, Inge Everaert, Wim Derave, Caroline Van den Broecke, Manon Huizing, Nezahat Bostan, Marijn Speeckaert, Nico Callewaert, Elisabeth Van Aken, Joris R. Delanghe
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:International Journal of Molecular Sciences
Subjects:
advanced glycation end products
cataract
deglycation
fructosamine-3-kinase
therapeutics
Online Access:https://www.mdpi.com/1422-0067/22/8/3841

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https://www.mdpi.com/1422-0067/22/8/3841

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