Use of functional respiratory imaging to characterize the effect of inhalation profile and particle size on lung deposition of inhaled corticosteroid/long-acting β2-agonists delivered a pressurized metered-dose inhaler

Background: Functional respiratory imaging (FRI) uses three-dimensional models of human lungs and computational fluid dynamics to simulate functional changes within airways and predict the deposition of inhaled drugs. This study used FRI to model the effects of different patient inhalation and drug...

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Bibliographic Details
Main Authors: Cedric Van Holsbeke, Jan De Backer, Wim Vos, Jonathan Marshall
Format: Article
Language:English
Published: SAGE Publishing 2018-02-01
Series:Therapeutic Advances in Respiratory Disease
Online Access:https://doi.org/10.1177/1753466618760948