Effects of recombinant human growth hormone treatment on growth, body composition, and safety in infants or toddlers with Prader-Willi syndrome: a randomized, active-controlled trial

Abstract Background Prader-Willi syndrome (PWS) is a rare complex genetic disorder and is characterized by short stature, muscular hypotonia, abnormal body composition, psychomotor retardation, and hyperphagia. Recombinant human growth hormone (rhGH) treatment improves the symptoms in children with...

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Bibliographic Details
Main Authors: Aram Yang, Jin-Ho Choi, Young Bae Sohn, Yunae Eom, Jiyoon Lee, Han-Wook Yoo, Dong-Kyu Jin
Format: Article
Published: BMC 2019-09-01
Series:Orphanet Journal of Rare Diseases
Online Access:http://link.springer.com/article/10.1186/s13023-019-1195-1