RANK promotes colorectal cancer migration and invasion by activating the Ca2+-calcineurin/NFATC1-ACP5 axis

Abstract The tumor necrosis factor (TNF) receptor superfamily member 11a (TNFRSF11a, also known as RANK) was demonstrated to play an important role in tumor metastasis. However, the specific function of RANK in colorectal cancer (CRC) metastasis and the underlying mechanism are unknown. In this stud...

Full description

Bibliographic Details
Main Authors: Qian Liang, Yun Wang, Yingsi Lu, Qingqing Zhu, Wenlin Xie, Nannan Tang, Lifen Huang, Tailai An, Di Zhang, Anqi Yan, Shaoyu Liu, Liping Ye, Chengming Zhu
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-03642-7