Identification of Genes in Candida glabrata Conferring Altered Responses to Caspofungin, a Cell Wall Synthesis Inhibitor

Identification of Genes in Candida glabrata Conferring Altered Responses to Caspofungin, a Cell Wall Synthesis Inhibitor

Candida glabrata is an important human fungal pathogen whose incidence continues to rise. Because many clinical isolates are resistant to azole drugs, the drugs of choice to treat such infections are members of the echinocandin family, although there are increasing reports of resistance to these dru...

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Bibliographic Details
Main Authors: Anne G. Rosenwald, Gaurav Arora, Rocco Ferrandino, Erica L. Gerace, Maedeh Mohammednetej, Waseem Nosair, Shemona Rattila, Amanda Zirzow Subic, Ronda Rolfes
Format: Article
Language:English
Published: Oxford University Press 2016-09-01
Series:G3: Genes, Genomes, Genetics
Subjects:
caspofungin
echinocandins
cell wall integrity pathway
high affinity calcium uptake system
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.116.032490

Internet

http://g3journal.org/lookup/doi/10.1534/g3.116.032490

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