Urolithin A Is a Dietary Microbiota-Derived Human Aryl Hydrocarbon Receptor Antagonist

Urolithins (e.g., UroA and B) are gut microbiota-derived metabolites of the natural polyphenol ellagic acid. Urolithins are associated with various health benefits, including attenuation of inflammatory signaling, anti-cancer effects and repression of lipid accumulation. The molecular mechanisms und...

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Bibliographic Details
Main Authors: Gulsum E. Muku, Iain A. Murray, Juan C. Espín, Gary H. Perdew
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:Metabolites
Subjects:
Online Access:https://www.mdpi.com/2218-1989/8/4/86