From reads to genes to pathways: differential expression analysis of RNA-Seq experiments using Rsubread and the edgeR quasi-likelihood pipeline [version 2; referees: 5 approved]

In recent years, RNA sequencing (RNA-seq) has become a very widely used technology for profiling gene expression. One of the most common aims of RNA-seq profiling is to identify genes or molecular pathways that are differentially expressed (DE) between two or more biological conditions. This article...

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Bibliographic Details
Main Authors: Yunshun Chen, Aaron T. L. Lun, Gordon K. Smyth
Format: Article
Language:English
Published: F1000 Research Ltd 2016-08-01
Series:F1000Research
Subjects:
Online Access:http://f1000research.com/articles/5-1438/v2