PGC-1α isoforms coordinate to balance hepatic metabolism and apoptosis in inflammatory environments

PGC-1α isoforms coordinate to balance hepatic metabolism and apoptosis in inflammatory environments

Objective: The liver is regularly exposed to changing metabolic and inflammatory environments. It must sense and adapt to metabolic need while balancing resources required to protect itself from insult. Peroxisome proliferator activated receptor gamma coactivator-1 alpha (PGC-1α) is a transcriptiona...

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Bibliographic Details
Main Authors: Mélissa Léveillé, Aurèle Besse-Patin, Nathalie Jouvet, Aysim Gunes, Sarah Sczelecki, Stewart Jeromson, Naveen P. Khan, Cindy Baldwin, Annie Dumouchel, Jorge C. Correia, Paulo R. Jannig, Jonathan Boulais, Jorge L. Ruas, Jennifer L. Estall
Format: Article
Language:English
Published: Elsevier 2020-04-01
Series:Molecular Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877820300065

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http://www.sciencedirect.com/science/article/pii/S2212877820300065

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