Mitochondrial-dependent Autoimmunity in Membranous Nephropathy of IgG4-related Disease

Mitochondrial-dependent Autoimmunity in Membranous Nephropathy of IgG4-related Disease

The pathophysiology of glomerular lesions of membranous nephropathy (MN), including seldom-reported IgG4-related disease, is still elusive. Unlike in idiopathic MN where IgG4 prevails, in this patient IgG3 was predominant in glomerular deposits in the absence of circulating anti-phospholipase A2 rec...

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Bibliographic Details
Main Authors: Simona Buelli, Luca Perico, Miriam Galbusera, Mauro Abbate, Marina Morigi, Rubina Novelli, Elena Gagliardini, Chiara Tentori, Daniela Rottoli, Ettore Sabadini, Takao Saito, Mitsuhiro Kawano, Takako Saeki, Carlamaria Zoja, Giuseppe Remuzzi, Ariela Benigni
Format: Article
Language:English
Published: Elsevier 2015-05-01
Series:EBioMedicine
Subjects:
IgG4-related disease
Membranous nephropathy
Carbonic anhydrase II
Superoxide dismutase 2
Podocyte
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396415000663

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http://www.sciencedirect.com/science/article/pii/S2352396415000663

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