Protein kinase Cbeta mediates hepatic induction of sterol-regulatory element binding protein-1c by insulin

Protein kinase Cbeta mediates hepatic induction of sterol-regulatory element binding protein-1c by insulin

Sterol-regulatory element binding protein-1c (SREBP-1c) is a transcription factor that controls lipogenesis in the liver. Hepatic SREBP-1c is nutritionally regulated, and its sustained activation causes hepatic steatosis and insulin resistance. Although regulation of SREBP-1c is known to occur at th...

Full description

Bibliographic Details
Main Authors: Takashi Yamamoto, Kazuhisa Watanabe, Noriyuki Inoue, Yoshimi Nakagawa, Naomi Ishigaki, Takashi Matsuzaka, Yoshinori Takeuchi, Kazuto Kobayashi, Shigeru Yatoh, Akimitsu Takahashi, Hiroaki Suzuki, Naoya Yahagi, Takanari Gotoda, Nobuhiro Yamada, Hitoshi Shimano
Format: Article
Language:English
Published: Elsevier 2010-07-01
Series:Journal of Lipid Research
Subjects:
SREBP
lipogenesis
fatty acid
triglyceride
glucose
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752037108X

Internet

http://www.sciencedirect.com/science/article/pii/S002222752037108X

Similar Items