Multi-Compartment, Early Disruption of cGMP and cAMP Signalling in Cardiac Myocytes from the <i>mdx</i> Model of Duchenne Muscular Dystrophy

Multi-Compartment, Early Disruption of cGMP and cAMP Signalling in Cardiac Myocytes from the <i>mdx</i> Model of Duchenne Muscular Dystrophy

Duchenne muscular dystrophy (DMD) is the most frequent and severe form of muscular dystrophy. The disease presents with progressive body-wide muscle deterioration and, with recent advances in respiratory care, cardiac involvement is an important cause of morbidity and mortality. DMD is caused by mut...

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Bibliographic Details
Main Authors: Marcella Brescia, Ying-Chi Chao, Andreas Koschinski, Jakub Tomek, Manuela Zaccolo
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:International Journal of Molecular Sciences
Subjects:
Duchenne muscular dystrophy
cAMP
cGMP
NO
phosphodiesterases
cardiomyopathy
Online Access:https://www.mdpi.com/1422-0067/21/19/7056

Internet

https://www.mdpi.com/1422-0067/21/19/7056

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