mTOR signaling pathway and mTOR inhibitors in the treatment of cancer
Mammalian target of rapamycin (mTOR) plays a majorrole in the regulation of protein translation, cell growth,and metabolism. Three basic signalling pathways thathave been described as important in cancer including thephosphatidylinositol 3-kinase (PI3K)/AKT/mTOR kinasecascade, the protein kinase C (...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Dicle University Medical School
2013-03-01
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| Series: | Dicle Medical Journal |
| Subjects: | |
| Online Access: | http://www.diclemedj.org/upload/sayi/26/Dicle%20Med%20J-01203.pdf |