Profiling of Parkin-binding partners using tandem affinity purification.

Parkinson's disease (PD) is a progressive neurodegenerative disorder affecting approximately 1-2% of the general population over age 60. It is characterized by a rather selective loss of dopaminergic neurons in the substantia nigra and the presence of α-synuclein-enriched Lewy body inclusions....

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Main Authors: Alessandra Zanon, Aleksandar Rakovic, Hagen Blankenburg, Nadezhda T Doncheva, Christine Schwienbacher, Alice Serafin, Adrian Alexa, Christian X Weichenberger, Mario Albrecht, Christine Klein, Andrew A Hicks, Peter P Pramstaller, Francisco S Domingues, Irene Pichler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3823883?pdf=render