Identification of a Polyketide Synthase Gene Responsible for Ascochitine Biosynthesis in Ascochyta fabae and Its Abrogation in Sister Taxa

Identification of a Polyketide Synthase Gene Responsible for Ascochitine Biosynthesis in Ascochyta fabae and Its Abrogation in Sister Taxa

Fungi produce a diverse array of secondary metabolites, many of which are of pharmacological importance whereas many others are noted for mycotoxins, such as aflatoxin and citrinin, that can threaten human and animal health. The polyketide-derived compound ascochitine, which is structurally similar...

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Bibliographic Details
Main Authors: Wonyong Kim, Judith Lichtenzveig, Robert A. Syme, Angela H. Williams, Tobin L. Peever, Weidong Chen
Format: Article
Language:English
Published: American Society for Microbiology 2019-09-01
Series:mSphere
Subjects:
ascochyta fabae
didymellaceae
ascochitine
citrinin
nonsense mutation
polyketide
secondary metabolite
Online Access:https://doi.org/10.1128/mSphere.00622-19

Internet

https://doi.org/10.1128/mSphere.00622-19

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