Streptolysin O Rapidly Impairs Neutrophil Oxidative Burst and Antibacterial Responses to Group A Streptococcus

Streptolysin O Rapidly Impairs Neutrophil Oxidative Burst and Antibacterial Responses to Group A Streptococcus

Group A Streptococcus (GAS) causes a wide range of human infections, ranging from simple pharyngitis to life-threatening necrotizing fasciitis and toxic shock syndrome. A globally disseminated clone of M1T1 GAS has been associated with an increase in severe, invasive GAS infections in recent decades...

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Bibliographic Details
Main Authors: Satoshi Uchiyama, Simon Döhrmann, Anjuli M. Timmer, Neha Dixit, Mariam Ghochani, Tamara Bhandari, John C. Timmer, Kimberly Sprague, Juliane Bubeck Wardenburg, Scott I Simon, Victor Nizet
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-11-01
Series:Frontiers in Immunology
Subjects:
Infection
Neutrophils
Streptococcus pyogenes
oxidative burst
group A streptococcus
neutrophil extracellular traps (NETs)
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00581/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00581/full

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